PREPARATION OF TOXOIDS FROM THE VENOMS OF PAKISTAN SPECIES OF SNAKES (NAJA NAJA, VIPERA RUSSELLII AND ECHIS CARINATUS)
نویسندگان
چکیده
منابع مشابه
Toxoiding of snake venom and evaluation of immunogenicity of the toxoids.
The venom of Pakistan species of snakes (Naja naja, Vipera russelli and Echis carinatus) and lethal fractions of Cobra (Naja naja) venom were converted to toxoid with formalin. Detoxification of the crude venoms and toxic fraction was attained by addition of formalin in several steps and incubation at 37°C maintaining the pH 7.0. Relationship of formalin concentration and incubation period was ...
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A combination of narrow range isoelectric focusing, electrophoresis on polyacrylamide gel, and gel exclusion on Sephadex reveals the presence of at least 9, possibly 11 isoenzymes of phospholipase A in Naja naja (cobra) venom. Their isoelectric points range from pH 4.60 to 5.66 and their molecular weights from 8,500 to 20,200. The most abundant form (isoelectric point = pH 4.95) has been isolat...
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A combination of narrow range isoelectric focusing, electrophoresis on polyacrylamide gel, and gel exclusion on Sephadex reveals the presence of at least 9, possibly 11 isoenzymes of phospholipase A in Naja naja (cobra) venom. Their isoelectric points range from pH 4.60 to 5.66 and their molecular weights from 8,500 to 20,200. The most abundant form (isoelectric point = pH 4.95) has been isolat...
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The venoms from central Asian snakes (Echis carinatus, Echis multisquamatus, Vipera ursini, Vipera lebetina, Agkistrodon halys halys and Naja naja oxiana) contain several enzymes with amidolytic- and procoagulant activity. We have characterized the activities and the mol. wts of the venom enzymes that are able to convert a number of commercially available chromogenic substrates for activated co...
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Cytogenetic studies were carried out on four species of Indian snakes viz Eryx conicus (Family Boidae), Naja naja naja (Family Elapidae), Vipera russelli and Echis carinatus (Family Viperidae) collected from Jammu region (J&K). Both E. conicus and N. n. naja show deviation from typical ophidian karyotype (2n=36), having 2n=34 (16 macroand 18 microchromosomes, NF=42) in E. conicus and 2n=38 (16 ...
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Science and Biology
سال: 1977
ISSN: 0021-5112,1884-2828
DOI: 10.7883/yoken1952.30.19